Table 1.

Current Stability Profile, Dose and Dosing Schedule of mRNA COVID-19 Vaccine Candidates in Development (Status December 05, 2020).

Manufacturer	Stability in Frozen State	Stability at 2–8 °C	Stability at Room Temperature	Dose (Injection Volume); Dosing Schedule	References
Moderna	−20 °C, up to 6 months	30 days	Up to 12 h	100 μg (0.5 mL); day 1, day 29	36,37
Pfizer-BioNTech	−80 °C to −60 °C, up to 6 months	up to 5 days	Up to 2 h (up to 6 h after dilutiona)	30 μg (0.3 mL); day 1, day 21	5,38,39
CureVac	≤ −60 °C, at least 3 months	At least 3 months	Up to 24 h	12 μg (no information); day 1, day 29	40, 41, 42

^aThe thawed vaccine must be diluted in its original multidose vial with unpreserved 1.8 mL sodium chloride 9 mg/mL (0.9%) solution for injection (not provided with the vaccine).³⁹