Table 2.
Comparison of Survivors to Nonsurvivors
| Variable | Survivors (n = 44) | Nonsurvivors (n = 10) | P value | Univariate OR (± CI) | P valuea | Multivariate ORs (+CI)b | P valuec | Rd |
|---|---|---|---|---|---|---|---|---|
| Age, mean (SD) | 55.05 (18.43) | 74.93 (15.36) | .003 | 1.07 (1.02, 1.12) | .007 | 1.06 (1.00,1.12) | .06 | 0.47 |
| 0.21 (0.06, 0.73) | .014 | … | ||||||
| Male (%) | 31 (70.5) | 6 (60.0) | .791 | … | … | … | … | … |
| Female (%) | 13 (29.5) | 4 (40.0) | … | … | … | … | … | … |
| BMI, mean (SD) | 26.36 (4.87) | 26.84 (4.61) | .821 | … | … | … | … | … |
| Medical background | ||||||||
| DM (%) | 14 (31.8) | 4 (40.0) | .901 | … | … | … | … | |
| … | ||||||||
| HTN (%) | 14 (31.8) | 7 (70.0) | .061 | 5.0 (1.12, 22.27) | .035 | 3.81 (0.69, 21.2) | .12 | 0.43 |
| 0.18 (0.05, 0.6) | .005 | … | ||||||
| CVA (%) | 5 (11.4) | 3 (30.0) | .315 | … | … | … | … | |
| IHD (%) | 2 (4.5) | 3 (30.0) | .057 | … | … | … | … | |
| … | ||||||||
| CHF (%) | 1 (2.3) | 2 (20.0) | .15 | … | … | … | … | |
| … | ||||||||
| Charlson index, mean (SD) | 2.48 (2.45) | 6.10 (2.13) | <.001 | 1.7 (1.22, 2.37) | .0017 | 1.48 (1.03, 2.14) | .035 | 0.49 |
| 0.27 (0.07, 0.97) | .04 | … | ||||||
| Thyroid hormones | ||||||||
| TSH (mIU/L) | 2.65 (2.65) | 3.37 (4.78) | .52 | 1.07 (0.87, 1.31) | .51 | … | … | |
| FT4 (pmol/L) | 13.14 (4.11) | 13.49 (3.53) | .5 | 1.02 (0.87, 1.21) | .8 | … | … | |
| FT3 (pmol/L) | 4.65 (0.93) | 3.45 (0.77) | <.001 | 0.17 (0.05, 0.54) | .003 | … | … | |
| Laboratory results | ||||||||
| Hb (g/dL) | 13.18 (2.23) | 11.87 (2.27) | .076 | 0.78 (0.58,1.06) | .11 | … | … | |
| WBC (K/μL) | 7.50 (3.34) | 14.66 (7.63) | .001 | 1.34 (1.11, 1.63) | .0026 | 1.28 (1.05, 1.56) | .013 | 0.58 |
| 0.2 (0.05, 0.72) | .015 | … | ||||||
| Neutrophils (K/μL) | 5.59 (2.90) | 12.86 (8.21) | .001 | 1.37 (1.12, 1.67) | .0024 | 1.3 (1.05, 1.61) | .015 | 0.58 |
| 0.2 (0.05,0.73) | .015 | … | ||||||
| Lymphocytes (K/μ) | 1.09 (0.60) | 0.84 (0.35) | .3 | 0.39 (0.09, 1.7) | .21 | … | … | … |
| … | ||||||||
| Albumin (g/dL) | 3.70 (0.55) | 2.79 (0.59) | <.001 | 0.02 (0.00, 0.25) | .003 | 0.01 (0.00, 0.3) | .01 | 0.67 |
| 0.15 (0.03, 0.83) | .03 | |||||||
| Cr (mg/dL) | 0.88 (0.42) | 1.40 (0.99) | .08 | 3.28 (1.09, 9.84) | .034 | 1.2 (0.33, 4.33) | .78 | 0.38 |
| 0.19 (0.05, 0.67) | .01 | … | ||||||
| LDH (IU/L) | 357.79 (182.22) | 489.90 (229.62) | .06 | 1.0 (0.00, 1.01) | .07 | … | … | … |
| … | ||||||||
| D-dimer (ng/mL) | 4330.38 (12521.36) | 11474.00 (19677.18) | .07 | 1.0 (0.99, 1.00) | .23 | … | … | … |
| … | ||||||||
| Ferritin (ng/mL) | 617.44 (651.16) | 521.40 (571.27) | .95 | 0.99 (0.99, 1.00) | .71 | … | … | … |
| … | ||||||||
| Troponin-I HS (ng/L) | 17.26 (17.17) | 213.45 (329.72) | <.001 | 1.05 (1.01, 1.10) | .02 | … | … | … |
| … | ||||||||
| CRP (mg/L) | 82.16 (88.61) | 143.30 (98.06) | .053 | 1.01 (0.99, 1.01) | .07 | … | … | … |
| … | ||||||||
| AST (IU/L) | 52.36 (36.11) | 84.1 (88.25) | .69 | 1.01 (0.9998, 1.02) | .1 | … | … | … |
| ALT (IU/L) | 35.2 (20.93) | 53.6 (61.24) | .8 | … | … | … | … | … |
| ED clinical parameters on presentation, mean (SD) | ||||||||
| Oxygen room air saturation (%) | 88.31 (14.40) | 85.90 (13.07) | .47 | … | … | … | … | … |
| HR (bpm) | 90.15 (17.48) | 95.50 (26.12) | .46 | … | … | … | … | … |
| RR (respirations/min) | 23.84 (10.26) | 27.33 (8.19) | .34 | … | … | … | … | … |
| Temperature (°C) | 37.73 (0.80) | 37.53 (0.67) | .5 | … | … | … | … | … |
| SBP (mm Hg) | 134.37 (18.35) | 138.70 (24.27) | .54 | … | … | … | … | …. |
| DBP (mm Hg) | 77.74 (10.49) | 82.30 (8.90) | .22 | … | … | … | … | … |
Abbreviations: ALT = alanine transaminase; AST = aspartate aminotransferase; BMI = body mass index; bpm = beats/min; CHF = congestive heart failure; Cr = creatinine; CRP = c-reactive protein; CVA = cerebrovascular accident; DBP = diastolic blood pressure; DM, Diabetes mellitus; FT3 = free triiodothyronine; FT4 = free thyroxine; Hb = hemoglobin; HR = heart rate; HS = high sensitivity; HTN, Hypertension; IHD = ischemic heart disease; LDH = lactate dehydrogenase; RR = respiratory rate; SBP = systolic blood pressure; TSH = thyroid stimulating hormone; WBC = white blood cell.
P value for univariate model.
In the Multivariate OR (CI) column, the first OR (CI) is for the covariate and the second is for FT3
P values for multivariate model (with FT3). The P value for FT3 is the second one for each model.
Nagelkerke R for Multivariate model (with FT3). R2 for a model with FT3 alone is 0.38.