Table 3.
Comparison Between the Study Cohort and Hospitalized Patients with Coronavirus 2019 Without Free Triiodothyronine Measurements
| Variable | Study cohort (n = 54) | Hospitalized patients not in study cohorta (n = 395) | P value |
|---|---|---|---|
| Age (mean (SD)) | 58.73 (19.40) | 57.29 (18.73) | .64 |
| Gender (%) | |||
| Male | 37 (68.5) | 228 (57.7) | .172 |
| Female | 17 (31.5) | 167 (42.3) | … |
| BMI, mean (SD) | 26.43 (4.78) | 27.41 (5.32) | .36 |
| Medical background | |||
| DM (%) | 18 (33.3) | 76 (19.2) | .027 |
| HTN (%) | 21 (38.9) | 135 (34.2) | .596 |
| CVA (%) | 8 (14.8) | 30 (7.6) | .13 |
| IHD (%) | 5 (9.3) | 30 (7.6) | .59 |
| CHF (%) | 3 (5.6) | 19 (4.8) | .74 |
| PVD (%) | 1 (1.9) | 13 (3.3) | 1 |
| Autoimmune disease (%) | 2 (3.7) | 23 (5.8) | .76 |
| Cognitive decline (%) | 10 (18.5) | 37 (9.4) | .07 |
| Charlson index, mean (SD) | 3.15 (2.77) | 2.66 (2.67) | .19 |
| Laboratory tests, mean (SD) | |||
| Hb (g/dL) | 12.94 (2.28) | 13.25 (1.88) | .52 |
| WBC (K/μL) | 8.85 (5.20) | 7.93 (26.73) | <.001 |
| Neutrophils (K/μL) | 6.94 (5.14) | 4.69 (3.08) | <.001 |
| Lymphocytes (K/μL) | 1.05 (0.57) | 1.19 (0.64) | .11 |
| PLT (K/μL) | 229.46 (116.47) | 194.95 (77.99) | .026 |
| Albumin (g/dL) | 3.54 (0.66) | 3.80 (0.51) | .002 |
| Cr (mg/dL) | 0.98 (0.59) | 0.90 (0.48) | .97 |
| AST (IU/L) | 58.24 (50.35) | 40.67 (28.42) | .003 |
| ALT (IU/L) | 38.61 (32.32) | 30.80 (26.57) | .02 |
| LDH (IU/L) | 382.72 (196.64) | 313.41 (128.85) | .018 |
| D-dimer (ng/mL) | 5691.07 (14154.82) | 1741.45 (5117.51) | .072 |
| Ferritin (ng/mL) | 601.80 (633.44) | 485.06 (600.04) | .5 |
| Troponin-I HS (ng/L) | 62.11 (172.03) | 55.24 (342.78) | <.001 |
| CRP (mg/L) | 93.69 (92.68) | 71.27 (75.10) | .19 |
| Study outcomes | |||
| Death cases (%) | 10 (18.5) | 14 (3.5) | <.001 |
| Mechanical ventilation (%) | 14 (25.9) | 3 (0.8) | <.001 |
| ICU (%) | 17 (31.5) | 14 (3.5) | <.001 |
| LOS (d), mean (SD) | 26.21 (31.67) | 7.41 (9.21) | <.001 |
Abbreviations: ALT = alanine transaminase; AST = aspartate aminotransferase; BMI = body mass index; CHF = congestive heart failure; Cr = creatinine; CRP = c-reactive protein; CVA = cerebrovascular accident; DM = diabetes mellitus; Hb = hemoglobin; HTN = hypertension; ICU = intensive care unit; IHD = ischemic heart disease; LDH = lactate dehydrogenase; LOS = length of stay; PLT = platelets; PVD = peripheral vascular disease.
a
Excluded patients who were excluded from the study and study cohort.