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. 2020 Dec 24;12(12):e12263. doi: 10.7759/cureus.12263

Table 1. Summary of clinical features and immunohistochemistry of the 22 cases of soft tissue tumours with epithelioid morphology.

IHC: Immunohistochemistry; INI 1: Integrase interactor 1; EMA: Epithelial membrane antigen; HMB-45: Human melanoma black; DOG1: Discovered on GIST1

Diagnosis Number of cases (n=22) Age (years) Site Size (cm) Positive  IHC Negative  IHC
Epithelioid Sarcoma (Conventional) 3 27 to 47 Lower extremities 5 to 25 Vimentin, cytokeratin and CD34   S100, CD99, desmin, smooth muscle actin and INI 1
Epithelioid Sarcoma (Proximal type) 2 Upper extremities
Malignant Extrarenal Rhabdoid Tumour 1 35 Scapula 4 Vimentin, cytokeratin and CD99 S100, desmin, CD34 and INI 1
Epithelioid malignant peripheral nerve sheath tumour 2 63 and 50 Chest and left leg 6 and 12 S-100 and vimentin Cytokeratin, EMA, desmin, CD34, Melan-A and HMB-45
Epithelioid Leiomyosarcoma 1 50 Left leg   Smooth muscle actin and vimentin Cytokeratin, CD34, S100, HMB-45 and CD117
Epithelioid angiosarcoma 3 40 to 65 Lower extremities 15 to 25 CD31 and factor VIII Cytokeratin, EMA and desmin
Sclerosing epithelioid fibrosarcoma 1 50 Left knee 12 Vimentin Cytokeratin, EMA, HMB45, desmin and alpha-smooth muscle actin
Epithelioid myxofibrosarcoma 3 43 to 45 Lower extremities 10 to 20 - All negative
Epithelioid gastrointestinal stromal tumour 2 48 and 58 Stomach and ileum 12 and 21 CD117 and DOG1 Cytokeratin, EMA, HMB45, desmin and alpha-smooth muscle actin
Clear cell sarcoma 2 17 and 35 Left thigh and chest wall 10 and 6 HMB-45, neuron-specific enolase and S-100 Cytokeratin, EMA, carcinoembryonic antigen, desmin, Melan-A and smooth muscle actin
Monophasic synovial sarcoma 1 50 Inguinal region 5 Cytokeratin, EMA and vimentin Smooth muscle actin, S100 and CD117
Malignant perivascular epithelioid cell tumour 1 50 Retroperitoneum 8 HMB45, Melan-A and actin Cytokeratin, S100 and CD117