Table 1.
Passively transferred therapeutic agents to prevent or treat infectious disease-related conditions in the form of intravenous immunoglobulin (IVIG) or monoclonal antibodies (Mab).
| Disease condition | Source |
|---|---|
| Anthrax | Human Mab |
| Bone-marrow transplantation | Human IVIGa |
| Botulism | Human IVIG |
| Common Variable Immunodeficiency | Human IVIGa |
| Diphtheria | Equine IVIG |
| Hepatitis A | Human IVIG |
| Hepatitis B | Human IVIG |
| Rabies | Human IVIG |
| Respiratory syncytial virus (RSV) infection | Human Mabb |
| Tetanus | Human IVIG; Equine IVIGc |
| Varicella | Human IVIG |
a
For pre-exposure prophylaxis; the other sources are for post-exposure treatment.
b
A Mab is used to treat RSV infection having replaced a previously used immune globulin.
c
The equine version is not typically used in the developed world due to the risk of serum sickness, but may be the only intervention available in developing countries.