Table 3.
Area under the ROC curve and optimal cut-off values of the immune inflammatory markers according to the severity.
| Variable | AUROC | Optimal cut-off value | Sensitivity | Specificity | OR (95%CI) |
|---|---|---|---|---|---|
| NLR | 0.831 | 5.9 | 71.7% | 80.3% | 8.7 (3.85–19.7) |
| d-NLR | 0.748 | 4.6 | 57% | 87% | 7.95 (3.36–18.83) |
| WBC | 0.693 | 9.67 × 103/µl | 63% | 83.1% | 8.11 (3.53–18.66) |
| NEU | 0.765 | 8.84 × 103/µl | 55% | 93% | 15.95 (5.54–45.94) |
| LYM | 0.737 | 0.9 × 103/µl | 51% | 88.7% | 8.30 (3.34–20.66) |
| IL6 | 0.972 | 44 pg/ml | 94.9% | 93.2% | 253.86 (58.11–1109) |
| PCT | 0.856 | 0.138 ng/ml | 76.3% | 79.5% | 12.42 (5.44–28.39) |
| CRP | 0.816 | 123 mg/l | 70% | 80.8% | 9.59 (4.29–21.45) |
| Ferritin | 0.752 | 601 ng/ml | 83.1% | 64.4% | 8.86 (3.85–20.35) |
| IL2Rα | 0.724 | 1204 U/ml | 54.2% | 83.6% | 6.02 (2.69–13.45) |
| IL6 + NLR | 0.98 | – | – | – | – |
The optimal discriminating cut-off values were obtained by calculating the Youden index. The Odds Ratio with their confidence intervals 95% were calculated according to the cut-off values by Fisher's exact test.
AUOC: Area under the receiver operating characteristic curve; CI: confidence interval; OR: odds ratio.