Table 2.

Bivariate and multivariate analysis of factors associated with serum cryptococcal antigenemia among HIV/AIDS patients in Felege-Hiwot Referral Hospital, Bahir Dar, Ethiopia.

Variable	Pos., N (%)	Neg., N (%)	P value	COR (95% CI)	P value	AOR (95% CI)
Sex
Male	7 (44)	52 (42)	1		1
Female	9 (56)	72 (58)	0.890	1 (0.377–3)	0.329	0.4 (0.05–2.7)
Age
15–24	3 (19)	16 (13)	0.300	0.4 (0.056–2.4)	0.268	0.2 (0.007–3.9)
25–44	11 (69)	76 (63)	0.354	0.5 (0.1–2.3)	0.586	0.6 (0.07–4.6)
>45	2 (12)	29 (24)	1
Marital status
Unmarried	6 (37.5)	33 (26.6)	0.745	0.8 (0.23–2.9)	0.637	1.7 (0.2–13)
Married	5 (31.2)	57 (46)	0.440	1.7 (0.45–6.2)	0.846	0.8 (0.1–6.3)
Others	5 (31.2)	34 (27.4)	1
Educational status
Illiterate	4 (25)	36 (29)	1	1
Literate	12 (75)	88 (71)	0.737	0.82 (025–2.7)	0.366	0.4 (0.04–3.2)
Occupation
Student	1 (6.2)	17 (14)	1		1
House wife	2 (12.5)	20 (16)	0.676	0.6 (0.05–7)	0.580	0.4 (0.012–12)
Employed	11 (68.8)	71 (57)	0.369	0.4 (0.05–3)	0.185	0.14 (0.008–2.6)
Jobless	2 (12.5)	16 (13)	0.554	0.5 (0.04–5.7)	0.340	0.19 (0.006–5.9)
Residence
Urban	9 (56)	91 (73.4)	0.160	2 (0.74–6)	0.831	1.3 (0.2–10)
Rural	7 (44)	33 (26.6)	1
Bacterial status (n = 79)
Pulmonary	7 (43.8)	7 (11.1)	0.001	0.08 (0.02–0.35)	0.001	0.04 (0.005–0.25)
Ex pulmonary	5 (31.2)	6 (9.5)	0.003	0.1 (0.02–0.46)	0.006	0.07 (0.01–0.47)
BSI	4 (25)	50 (79.4)	1
CD4 status
<100	11 (68.7)	7 (5.6)	0.007	0.05 (0.005–0.4)	0.108	0.04 (0.001–2)
100–150	3 (18.7)	31 (25)	0.800	0.74 (0.07–7.7)	0.343	4.6 (0.2–110)
151–200	1 (6.3)	14 (11.3)	1
>200	1 (6.3)	72 (59.4)	0.257	5 (0.3–87)	0.096	31 (0.54–1865)
ART status
On ART	3 (18.8)	67 (54)	1
ART naïve	5 (31.2)	38 (30.6)	0.155	0.34 (0.07–1.5)	0.161	0.09 (0.004–2.5)
ART defaulter	8 (50)	19 (15.3)	0.002	0.1 (0.026–0.44)	0.019	0.02 (0.001–0.5)

Note. 1 = as a reference; others, widow and divorced; BSI, bacterial infection isolated by blood culture; AOR, adjusted odds ratio; OR, crude odds ratio; CI, confidence interval.