Skip to main content
. 2021 Jan 18;2021:8819884. doi: 10.1155/2021/8819884

Figure 2.

Figure 2

Effect of SHED transplantation on neuropathic pain. (a) Scheme showing the timing of SHED transplantation and behavioral testing. (b) The mechanical threshold was significantly decreased in CCI-ION rats. (c) Changes in the mechanical threshold after direct injection of low-dose (1 × 105 cells, 0.2 mL, CCI-ION+low-dose injSHED group) or high-dose (1 × 106 cells, 0.2 mL, CCI-ION+high-dose injSHED group) SHED into the site of injury were measured for 56 days in CCI-ION rats. Local injection of medium (CCI-ION+injMedium group) was used as a control. (d) Changes in the mechanical threshold after infusion of SHED (1 × 105 cells, 0.2 mL, CCI-ION+infSHED group) through the tail vein were measured for 56 days in CCI-ION rats. Infusion of medium (CCI-ION+infMedium group) was used as a control. ∗p < 0.05 vs. sham (b), ∗p < 0.05 vs. medium (c, d), and #p < 0.05 vs. day 0. All data are expressed as the mean ± SEM (n = 6 rats in each group).