Figure 4.
Local injection of SHED inhibits inflammatory cell infiltration in the injured nerve. (a) Scheme showing the timing of SHED transplantation and tissue collection. Hematoxylin-eosin staining revealed that the number of leukocytes recruited in the trigeminal nerve was significantly increased in the CCI-ION group (c) as compared with the sham group (b). Inflammatory cell infiltration in the trigeminal nerve was decreased after local injection of SHED (1 × 105 cells, 0.2 mL) (d). Scale bar = 200 μm.