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. 2021 Jan 7;47(3):14. doi: 10.3892/ijmm.2021.4847

Table III.

Targeting the PI3K-AKT pathway.

Inhibitor Target Function
GSK690693 AKT AKT Inhibitor
SF-1126 PI3K, mTOR PI3K pathway inhibitor
AZD8055 mTOR mTOR inhibitor
Everolimus mTOR mTOR inhibitor
BGT226 mTOR, PI3Kα/β/γ PI3K/mTOR inhibitor
CAL-101 P110γ/δ P110 inhibitor
Perifosine AKT AKT inhibitor
MK2206 AKT AKT inhibitor
OSI027 mTOR mTOR kinase inhibitor
Alpelisib PI3Kα PI3Kα inhibitor