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International Journal of Molecular Medicine logoLink to International Journal of Molecular Medicine
. 2021 Jan 11;47(3):18. doi: 10.3892/ijmm.2021.4851

Rab22a is a novel prognostic marker for cell progression in breast cancer

Miao He, Leihua Shen, Chengwei Jiang, Ge Gao, Keren Wang, Yan Jiao, Liang Sun, Yingnan Cui, Zirui Ke, Zhaoying Yang
PMCID: PMC7834961  PMID: 33655335

Int J Mol Med 45: 1037-1046, 2020; DOI: 10.3892/ijmm.2020.4486

Following the publication of this article, the authors have realized that Table I contained an error: The number of patients who were alive in the Rab22a high expression group should have been written as 77 instead of 772.

Table I.

Clinicopathological characteristics of patient samples and expression of Rab22a in breast cancer.

Characteristics Rab22a expression
P-value
Low Middle High
Age, years
 <50 20 58 45
 ≥50 10 67 58 0.079
Menopause stage
 No 20 68 55
 Yes 10 57 48 0.415
Age at menarche, years
 <15 19 71 39
 ≥15 11 54 64 0.005
Clinical stage
 I 17 49 32
 II 7 57 34
 III 6 19 37 0.001
T classification
 T1 22 80 53
 T2 8 40 40
 T3 0 5 9
 T4 0 0 1 0.148
N classification
 N0 19 71 47
 N1 5 35 22
 N2 2 13 13
 N3 4 6 21 0.013
Nipple invasion
 No 30 124 97
 Yes 0 1 6 0.042
Venous invasion
 No 23 90 60
 Yes 7 35 43 0.044
Nerve invasion
 No 26 99 82
 Yes 4 26 21 0.640
Basal invasion
 No 30 124 101
 Yes 0 1 2 0.595
Pectoralis minor muscle invasion
 No 30 124 101
 Yes 0 1 2 0.595
Pathological differentiation
 G1 4 10 7
 G2 23 85 73
 G3 3 30 23 0.446
ER status
 Negative 5 32 33
 Positive 25 93 70 0.216
PR status
 Negative 6 41 40
 Positive 24 84 63 0.151
Expression of Her-2
 Negative 22 91 63
 Positive 8 34 40 0.140
Expression of Ki67
 Low expression 24 88 64
 High expression 6 37 39 0.139
Molecular classification
 Luminal A 15 48 24
 Luminal B (Her-2-) 7 21 25
 Luminal B (Her-2+) 3 25 23
 Her-2+ 3 13 16
 Basal like 2 18 15 0.131
Vital status (at follow-up)
 Alive 28 112 77
 Dead 2 13 26 0.003

T, tumor; M, metastasis; N, node; ER, estrogen receptor; PR, progesterone receptor; Her-2, human epidermal growth factor-2.

A corrected version of the Table is shown on the next page (the corrected datum is highlighted in bold). The authors sincerely apologize for the error that was introduced during the preparation of this Table, and regret any inconvenience that this mistake has caused.


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