Figure 4.

Impact of exercise on a senescence marker, p16 and energy regulating enzyme in adipose tissues of aged mice. (A) p16 and GAPDH were measured through immuno-blotting in the white adipose tissue (WAT) of both young and old mice after 4-week of treadmill exercise or sedentariness. Representative 3 samples per group are shown (total n=5, each group). (B) Bar graph depicts the mean (± standard error of the mean, SEM) intensity ratio of p16 to GAPDH bands measured using ImageJ program. *p < 0.05 compared to old sedentary controls, **p < 0.01 compared to young sedentary controls or exercise groups.