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. 2021 Jan 6;13(1):1294–1313. doi: 10.18632/aging.202312

Table 1. NK cell mediated cytotoxicity related genes among DEGs in old exercise (OE) group compared to old control (OC) group. List of (A) up-regulated genes and (B) down-regulated genes.

A Up-regulated genes
Gene name Description
Cd48 CD48 antigen (Cd48)
Fcer1g Fc receptor, IgE, high affinity I, gamma polypeptide (Fcer1g)
Fcgr4 Fc receptor, IgG, low affinity IV (Fcgr4)
Tyrobp TYRO protein tyrosine kinase binding protein (Tyrobp)
Ifngr2 interferon gamma receptor 2 (Ifngr2)
Ncr1 natural cytotoxicity triggering receptor 1 (Ncr1)
Rac2 RAS-related C3 botulinum substrate 2 (Rac2)
Itgb2 integrin beta 2 (Itgb2)
Lcp2 lymphocyte cytosolic protein 2 (Lcp2)
Nfatc2 nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2 (Nfatc2)
Pik3cg phosphoinositide-3-kinase, catalytic, gamma polypeptide (Pik3cg)
Prkcb protein kinase C, beta (Prkcb)
Vav1 vav 1 oncogene (Vav1)
B Down-regulated genes
Gene name Description
Cd244 CD244 natural killer cell receptor 2B4(Cd244)
Casp3 caspase 3(Casp3)
Gzmb granzyme B(Gzmb)
Pik3r3 phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55) (Pik3r3)