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. 2020 Nov 26;13(1):675–693. doi: 10.18632/aging.202173

Table 1. The IRGs in the immunoscore model associated with OS in the TCGA dataset.

Symbol Univariate Cox regression analysis LASSO coefficient
HR 95%CI P-value
SPP1 1.139 1.080-1.201 1.49e-06 0.0252
STC2 1.382 1.206-1.585 3.29e-06 0.0964
HSPA8 1.569 1.233-1.996 0.000249 0.0763
IL15RA 1.546 1.257-1.903 3.78e-05 0.0673
BLNK 0.711 0.575-0.879 0.001629 -0.0102
TRAF3 1.664 1.222-2.267 0.001237 0.1197
NOD2 1.469 1.141-1.890 0.002833 0.0486
GRB2 2.150 1.437-3.216 0.000195 0.0485
ACTG1 1.525 1.249-1.863 3.54e-05 0.0262
HDAC1 1.933 1.435-2.603 1.43e-05 0.1284
S100A9 1.288 1.172-1.417 1.76e-07 0.0587
PSMD1 2.886 1.815-4.588 7.42e-06 0.2254
EPO 1.285 1.162-1.420 9.35e-07 0.0855

Abbreviations: IRGs, immune-related genes; OS, overall survival; TCGA, The Cancer Genome Atlas; HR, hazard ratio; CI, confidence interval; LASSO, the Least Absolute Shrinkage and Selection Operator.