Table 3. Univariate and multivariate Cox regression analysis of TCGA-LIHC patients.
| Characteristics | Univariate Cox | Multivariate Cox | ||
| HR (95%CI) | P | HR (95%CI) | P | |
| Immunoscore | 7.372 (3.995 – 13.605) | <0.001 | 5.917 (3.034 – 11.539) | < 0.001 |
| Age (years) | ||||
| < 60 | 1 | 1 | ||
| ≥ 60 | 1.392 (0.819 - 2.367) | 0.222 | 1.057 (0.589 – 1.899) | 0.852 |
| Sex | ||||
| Female | 1 | 1 | ||
| Male | 0.648 (0.380 - 1.105) | 0.111 | 0.911 (0.508 - 1.634) | 0.755 |
| BMI (kg/m2) | ||||
| < 25 | 1 | - | - | |
| ≥ 25 | 1.318 (0.779 – 2.229) | 0.303 | - | - |
| G stage | ||||
| G1 + G2 | 1 | 1 | ||
| G3 + G4 | 1.578 (0.931 - 2.676) | 0.090 | 1.204 (0.680 - 2.133) | 0.524 |
| Residual tumor | ||||
| R0 | 1 | - | - | |
| Non - R0 | 1.023 (0.247 - 4.237) | 0.975 | - | - |
| AJCC stage | ||||
| I + II | 1 | 1 | ||
| III + IV | 2.664 (1.529 – 4.642) | 0.001 | 2.229 (1.242 – 3.999) | 0.007 |
| Vascular invasion | ||||
| No | 1 | 1 | ||
| Yes | 2.035 (1.182 – 3.505) | 0.010 | 1.433(0.822 - 2.499) | 0.205 |
| AFP (ng/ml) | ||||
| < 300 | 1 | - | - | |
| ≥ 300 | 1.392 (0.819 - 2.367) | 0.222 | - | - |
Abbreviations: TCGA LIHC, The Cancer Genome Atlas Liver Hepatocellular Carcinoma; HR, hazard ratio; CI, confidence interval; BMI, body mass index; AJCC, The American Joint Committee on Cancer.