Table 1. Randomised controlled trials included in the systematic review and network meta-analysis.

Study	Trials	Clinical trial cycle (months)	data cutoff	Trial phase	No. of center	BRCA mutation type	HR	Stage of breast cancer	previous chemotherapy regimens for metastatic disease	previous cytotoxic regimens for advanced breast cancer
Robson et al.2017	OlympiAD	15	Dec.9, 2016	III	18	BRCA1/BRCA2/both	positive/negative	metastatic breast cancer	no more than two	unknown
Litton et al.2018	EMBRACA	42	Sep.15, 2017	III	16	BRCA1/BRCA2	positive/negative	metastatic or local advanced breast cancer	unknown	no more than three