Table 2. Characteristics of eligible studies.
Trials | Sample sizes | Age range | Drug type | Dosage and frequency | Crossover from control group to experimental group | ||||
Experiment | control | Experiment | control | Experiment | control | Experiment | control | ||
OlympiAD | 205 | 97 | 22–76 | 24–68 | Olaparib | PTC | 300 mg twice daily | standard therapy: eribulin mesylate administered intravenously at a dose of 1.4 mg on day 1 and day 8, repeated every 21 days; or vinorelbine administered intravenously at a dose of 30 mg on day 1 and day 8, repeated every 21 days. | not permitted |
EMBRACA | 287 | 144 | 27–84 | 24–88 | Talazoparib | PTC | 1 mg orally once daily continuously | standard-therapy: capecitabine, eribulin, gemcitabine, or vinorelbine in continuous 21-day cycles | not permitted |
PTC: Standard-Therapy Group.