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. 2020 Nov 30;13(1):450–459. doi: 10.18632/aging.202152

Table 2. Characteristics of eligible studies.

Trials Sample sizes Age range Drug type Dosage and frequency Crossover from control group to experimental group
Experiment control Experiment control Experiment control Experiment control
OlympiAD 205 97 22–76 24–68 Olaparib PTC 300 mg twice daily standard therapy: eribulin mesylate administered intravenously at a dose of 1.4 mg on day 1 and day 8, repeated every 21 days; or vinorelbine administered intravenously at a dose of 30 mg on day 1 and day 8, repeated every 21 days. not permitted
EMBRACA 287 144 27–84 24–88 Talazoparib PTC 1 mg orally once daily continuously standard-therapy: capecitabine, eribulin, gemcitabine, or vinorelbine in continuous 21-day cycles not permitted

PTC: Standard-Therapy Group.