Table 1. Association between the ERG signature and OS of patients with LUAD in the training set (TCGA, n = 490), stratified by demographic and clinical characteristics.

Characteristics	Number (high-/low-risk group)	Proportion of patients	HR (95% CI)	P-value
Age (years)
≥ 65	124/147	55.3%	0.554 (0.445–0.688)	0.000
< 65	121/98	44.7%	0.509 (0.306–0.849)	0.010
Sex
Female	116/150	54.3%	0.450 (0.290–0.698)	0.000
Male	129/95	45.7%	0.592 (0.457–0.765)	0.000
Stage
I	107/154	53.3%	0.654 (0.499–0.858)	0.002
II	70/47	23.9%	0.731 (0.537–0.995)	0.046
III	51/28	16.1%	0.673 (0.470–0.962)	0.030
IV	16/9	5.1%	0.611 (0.322–1.159)	0.132
NA	1/7	1.6%	−	−
T stage
T1	63/103	21.6%	0.744 (0.545–1.016)	0.063
T2	142/116	52.7%	0.667 (0.534–0.833)	0.000
T3	29/16	9.2%	0.233 (0.084–0.643)	0.005
T4	10/8	3.7%	0.500 (0.224–1.114)	0.090
NA	½	0.6%	−	−
M stage
M0	158/164	65.7%	0.644 (0.527–0.787)	0.000
M1	16/8	4.9%	0.518 (0.243–1.103)	0.088
NA	71/73	29.4%	−	−
N stage
N0	141/176	64.7%	0.589 (0.463–0.749)	0.000
N1	57/35	18.8%	0.811 (0.600–1.096)	0.173
N2	45/23	13.9%	0.777 (0.531–1.138)	0.195
N3	0/2	0.4%	−	−
NA	2/9	2.2%	−	−

NA, not available; HR, hazard ratio; CI, confidence interval.