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. 2020 Nov 21;13(1):351–363. doi: 10.18632/aging.104204

Table 1. Identification of TMB-related immune genes and the univariate Cox regression analysis in BRCA.

Gene HR HR.95L HR.95H CoxPvalue
ADRB1* 0.824 0.688 0.987 0.035
SEMA6D* 1.041 1.009 1.074 0.011
FGF14* 1.052 1.006 1.101 0.025
SCG2 1.004 1.002 1.006 9.936
CXCL14 0.999 0.999 1.000 0.320
TMSB15A 1.006 0.992 1.020 0.352
UMODL1 0.966 0.766 1.219 0.775
TNFSF11 0.992 0.951 1.035 0.742
CHGA 0.997 0.990 1.004 0.528
RLN2 1.001 0.986 1.015 0.892
STC2 1.000 0.999 1.001 0.787
TAC1 0.894 0.677 1.179 0.428
ULBP1 1.113 0.977 1.268 0.104
RAET1L 1.074 0.984 1.173 0.107
PDIA2 0.988 0.784 1.274 0.924
SLPI 1.000 0.999 1.000 0.807
LCN2 0.999 0.998 1.001 0.984
S100A9 0.999 0.999 1.000 0.586
S100A8 0.999 0.999 1.000 0.740
MMP12 1.003 0.985 1.020 0.722
PGLYRP4 1.036 0.874 1.229 0.677
FABP6 1.034 0.984 1.087 0.178
MUC5AC 1.003 0.998 1.007 0.145
MARCO 0.992 0.974 1.011 0.430
PCSK1 1.000 0.999 1.001 0.470
VTN 1.003 0.991 1.015 0.557
CCL14 0.898 0.722 1.117 0.336
CMA1 0.995 0.852 1.163 0.958
FGF10 1.001 0.995 1.008 0.641
CX3CR1 0.987 0.941 1.034 0.589
CHGB 1.000 0.999 1.000 0.080
EPO 1.007 0.978 1.037 0.594
GDNF 1.007 0.981 1.032 0.589
GHRH 0.992 0.939 1.047 0.781
NRTN 1.000 0.942 1.062 0.987
NTS 0.988 0.965 1.011 0.307
PTHLH 0.996 0.985 1.008 0.611
SLURP1 1.020 0.993 1.049 0.136
CRLF1 0.994 0.976 1.013 0.557
FGFR4 1.010 0.993 1.027 0.216
IL12RB2 0.955 0.844 1.081 0.472
IL1RL1 1.012 0.909 1.127 0.816
IL22RA2 0.758 0.536 1.071 0.116
PGR 0.996 0.985 1.008 0.583

*, coxPvalue< 0.05.