Table 1. Identification of TMB-related immune genes and the univariate Cox regression analysis in BRCA.
Gene | HR | HR.95L | HR.95H | CoxPvalue |
ADRB1* | 0.824 | 0.688 | 0.987 | 0.035 |
SEMA6D* | 1.041 | 1.009 | 1.074 | 0.011 |
FGF14* | 1.052 | 1.006 | 1.101 | 0.025 |
SCG2 | 1.004 | 1.002 | 1.006 | 9.936 |
CXCL14 | 0.999 | 0.999 | 1.000 | 0.320 |
TMSB15A | 1.006 | 0.992 | 1.020 | 0.352 |
UMODL1 | 0.966 | 0.766 | 1.219 | 0.775 |
TNFSF11 | 0.992 | 0.951 | 1.035 | 0.742 |
CHGA | 0.997 | 0.990 | 1.004 | 0.528 |
RLN2 | 1.001 | 0.986 | 1.015 | 0.892 |
STC2 | 1.000 | 0.999 | 1.001 | 0.787 |
TAC1 | 0.894 | 0.677 | 1.179 | 0.428 |
ULBP1 | 1.113 | 0.977 | 1.268 | 0.104 |
RAET1L | 1.074 | 0.984 | 1.173 | 0.107 |
PDIA2 | 0.988 | 0.784 | 1.274 | 0.924 |
SLPI | 1.000 | 0.999 | 1.000 | 0.807 |
LCN2 | 0.999 | 0.998 | 1.001 | 0.984 |
S100A9 | 0.999 | 0.999 | 1.000 | 0.586 |
S100A8 | 0.999 | 0.999 | 1.000 | 0.740 |
MMP12 | 1.003 | 0.985 | 1.020 | 0.722 |
PGLYRP4 | 1.036 | 0.874 | 1.229 | 0.677 |
FABP6 | 1.034 | 0.984 | 1.087 | 0.178 |
MUC5AC | 1.003 | 0.998 | 1.007 | 0.145 |
MARCO | 0.992 | 0.974 | 1.011 | 0.430 |
PCSK1 | 1.000 | 0.999 | 1.001 | 0.470 |
VTN | 1.003 | 0.991 | 1.015 | 0.557 |
CCL14 | 0.898 | 0.722 | 1.117 | 0.336 |
CMA1 | 0.995 | 0.852 | 1.163 | 0.958 |
FGF10 | 1.001 | 0.995 | 1.008 | 0.641 |
CX3CR1 | 0.987 | 0.941 | 1.034 | 0.589 |
CHGB | 1.000 | 0.999 | 1.000 | 0.080 |
EPO | 1.007 | 0.978 | 1.037 | 0.594 |
GDNF | 1.007 | 0.981 | 1.032 | 0.589 |
GHRH | 0.992 | 0.939 | 1.047 | 0.781 |
NRTN | 1.000 | 0.942 | 1.062 | 0.987 |
NTS | 0.988 | 0.965 | 1.011 | 0.307 |
PTHLH | 0.996 | 0.985 | 1.008 | 0.611 |
SLURP1 | 1.020 | 0.993 | 1.049 | 0.136 |
CRLF1 | 0.994 | 0.976 | 1.013 | 0.557 |
FGFR4 | 1.010 | 0.993 | 1.027 | 0.216 |
IL12RB2 | 0.955 | 0.844 | 1.081 | 0.472 |
IL1RL1 | 1.012 | 0.909 | 1.127 | 0.816 |
IL22RA2 | 0.758 | 0.536 | 1.071 | 0.116 |
PGR | 0.996 | 0.985 | 1.008 | 0.583 |
*, coxPvalue< 0.05.