Table 2. Laboratory findings of younger and elderly deceased patients with COVID-19 on admission.
| Characteristics | Total (n=163) | Younger(n=86) | Elderly(n=77) | P value |
| White blood cell count, ×109/L | 7.9 (5.5-10.8) | 7.4 (5.3-10.4) | 8.3 (5.9-10.9) | 0.302* |
| Red blood cell count, ×1012/L | 4.1 (3.8-4.5) | 4.1 (3.8-4.5) | 4.1 (3.7-4.5) | 0.400* |
| Hemoglobin, g/L | 126.8 (± 20.0) | 126.6 (± 19.1) | 127.1 (± 21.2) | 0.867† |
| Platelet count, ×109/L | 163.50 (116.25-231.50) | 164.50 (109.50-231.50) | 161.50 (122.00-232.00) | 0.905* |
| Neutrophil count, ×109/L | 7.01 (4.50-9.72) | 6.58 (4.31-9.30) | 7.23 (4.68-9.98) | 0.335* |
| Lymphocyte count, ×109/L | 0.62 (0.46-0.82) | 0.57 (0.44-0.83) | 0.64 (0.48-0.82) | 0.309* |
| NLR | 10.58 (6.77-16.58) | 10.60 (6.56-16.76) | 10.47 (6.96-16.03) | 0.954* |
| Monocyte count, ×109/L | 0.30 (0.20-0.48) | 0.30 (0.19-0.47) | 0.30 (0.21-0.50) | 0.554* |
| Eosinophil count, ×109/L | 0.00 (0.00-0.02) | 0.00 (0.00-0.01) | 0.01 (0.00-0.04) | 0.019* |
| Basophil count, ×109/L | 0.02 (0.01-0.03) | 0.02 (0.00-0.03) | 0.02 (0.01-0.03) | 0.916* |
| Total bilirubin, μmol/L | 13.45 (9.50-20.73) | 12.85 (9.20-20.05) | 14.35 (9.83-21.30) | 0.562* |
| Direct bilirubin, μmol/L | 4.90 (3.30-8.50) | 4.80 (3.30-8.35) | 5.10 (3.50-8.70) | 0.719* |
| Alanine aminotransferase, U/L | 36.00 (23.25-53.75) | 36.50 (25.50-55.50) | 35.50 (18.50-50.00) | 0.193* |
| Aspartate aminotransferase, U/L | 44.00 (31.00-61.75) | 44.00 (31.00-61.00) | 43.50 (29.00-64.50) | 0.621* |
| Alkaline phosphatase, U/L | 69.50 (48.25-93.00) | 72.00 (48.25-91.75) | 66.00 (48.25-94.75) | 0.631* |
| γ-glutamyl transpeptidase, U/L | 41.00 (24.25-81.75) | 37.00 (25.25-94.50) | 44.50 (23.25-71.00) | 0.973* |
| Total protein, g/L | 61.30 (57.83-64.58) | 60.95 (57.28-65.18) | 61.90 (58.30-64.40) | 0.798* |
| Albumin, g/L | 28.13 (± 5.00) | 27.99 (± 4.67) | 28.30 (± 5.38) | 0.701† |
| Globin, g/L | 33.20 (29.15-37.53) | 32.40 (29.30-37.68) | 33.85 (28.95-37.50) | 0.965* |
| Albumin/globin | 0.80 (0.70-1.00) | 0.85 (0.70-1.00) | 0.80 (0.70-1.00) | 0.890* |
| Prealbumin, mg/L | 85.45 (65.83-126.88) | 88.20 (69.10-129.10) | 83.80 (58.75-121.85) | 0.117* |
| Total bile acid, μmol/L | 3.20 (2.00-5.70) | 3.05 (1.75-4.40) | 3.75 (2.18-6.60) | 0.056* |
| Creatinine, μmol/L | 75.4 (63.35-95.70) | 71.90 (56.93-87.98) | 80.95 (71.10-112.15) | 0.001* |
| Blood urea nitrogen, mmol/L | 7.02 (5.06-10.47) | 6.91 (4.41-9.16) | 7.94 (5.43-13.94) | 0.016* |
| Uric acid, μmol/L | 235.05 (173.25-331.03) | 211.10 (158.75-272.70) | 273.95 (199.38-381.05) | <0.001* |
| Glucose, mmol/L | 7.57 (6.26-11.02) | 7.93 (6.50-11.78) | 6.99 (5.87-10.07) | 0.066* |
| Creatine kinase, U/L | 132.00 (68.50-262.00) (n=134) | 111.00 (71.00-207.25) (n=72) | 160.00 (57.50-311.75) (n=62) | 0.326* |
| Lactate dehydrogenase, U/L | 476.00 (358.00-591.00) | 497.00 (381.00-597.75) | 472.00 (338.00-586.00) | 0.604* |
| C-reactive protein, mg/L | 68.88 (± 43.86) | 69.73 (± 44.45) | 67.92 (± 43.47) | 0.799† |
| Procalcitonin, ng/mL | 0.26 (0.14-0.45) (n=114) | 0.23 (0.11-0.41) (n=60) | 0.35 (0.14-0.76) (n=54) | 0.075* |
| D-dimer, μg/mL | 2.31 (0.68-8.00) (n=137) | 2.68 (0.81-8.00) (n=72) | 2.07 (0.58-8.00) (n=65) | 0.441* |
| Prothrombin time, seconds | 14.20 (13.00-15.30) (n=147) | 14.20 (12.90-15.40) (n=79) | 14.20 (13.10-15.10) (n=68) | 0.529* |
| International normalized ratio | 1.12 (1.00-1.24) (n=148) | 1.12 (1.00-1.24) (n=79) | 1.12 (1.01-1.24) (n=69) | 0.470* |
| Activated partial thromboplastin time, seconds | 39.19 (± 8.78) (n=149) | 37.65 (± 7.89) (n=79) | 40.93 (± 9.45) (n=70) | 0.022† |
| Fibrinogen, g/l | 4.49 (3.20-5.25) (n=149) | 4.53 (3.20-5.38) (n=79) | 4.44 (3.20-5.25) (n=70) | 0.666* |
| Thrombin time, seconds | 15.80 (14.95-17.25) (n=149) | 15.70 (14.90-16.90) (n=79) | 15.80 (15.00-17.30) (n=70) | 0.725* |
| Brain natriuretic peptide, pg/ml | 98.60 (39.90-185.40) (n=89) | 95.50 (39.60-144.80) (n=47) | 102.75 (41.15-206.13) (n=42) | 0.562* |
| Myoglobin, ng/ml | 127.80 (62.85-287.05) (n=85) | 98.85 (48.90-222.63) (n=44) | 171.70 (85.25-548.60) (n=41) | 0.015* |
| Creatine kinase-MB, ng/ml | 1.70 (0.90-5.73) (n=92) | 1.50 (0.80-4.80) (n=49) | 3.00 (0.90-7.00) (n=43) | 0.120* |
| Hypersensitive cardiac troponin Ι, ng/L | 23.10 (8.78-114.18) (n=92) | 15.30 (7.30-86.40) (n=47) | 41.60 (12.75-436.65) (n=45) | 0.017* |
Note: data are presented as mean (± SD), medians (interquartile ranges, IQR) and medians (interquartile ranges, IQR) (n). P values are calculated by Wilcoxon rank-sum test or independent group t test, as appropriate.
Abbreviations: NLR, neutrophil-to-lymphocyte ratio.
*Calculated using the Wilcoxon rank-sum test.
†Calculated using the independent group t test.