Table 1. Demographic characteristics, clinical measures, and head rotation parameters of SCD subjects and CN.
| Items | CN | SCD | ||
| n=55 | n=38 | |||
| Age (years) | 62.91(5.94) | 65.84(7.73) | ||
| Gender (male/female) | 23/32 | 8/30 | ||
| Education level (years) | 12.51(2.51) | 12.22(2.72) | ||
| MMSE | 28.58(1.43) | 28.32(2.63) | ||
| MoCA | 25.05(2.42) | 24.92(1.79) | ||
| MDRS | 141.46(2.33) | 140.37(3.05) | ||
| HAMD | 1.82(2.26) | 3.92(3.17) a | ||
| SCD-Q | 3.55(1.50) | 6.51(0.90) a | ||
| ITV | 1130.24(114.65) | 1083.55(109.21) a | ||
| Episodic memory tests | ||||
| AVLT-IR | range | 10~31 | 11~28 | |
| raw score | 19.15(4.36) | 18.66(4.22) | ||
| Z score | 0.35(0.94) | 0.25(0.91) | ||
| AVLT-5min-DR | range | 0~11 | 3~10 | |
| raw score | 6.35(2.20) | 6.26(1.90) | ||
| Z score | 0.34(0.93) | 0.31(0.80) | ||
| AVLT-20min-DR | range | 2~10 | 3~11 | |
| raw score | 6.30(1.94) | 6.32(2.12) | ||
| Z score | 0.40(0.73) | 0.41(0.80) | ||
| AVLT-total | range | 17~51 | 19~48 | |
| raw score | 31.79(7.61) | 31.24(7.39) | ||
| Composite Z scores of each cognitive domain | ||||
| Episodic memory | 0.27(0.53) | 0.34(0.59) | ||
| Information processing speed | 0.27(0.67) | 0.18(0.71) | ||
| Executive function | 0.27(0.48) | 0.30(0.57) | ||
| Visuospatial function | 0.17(0.66) | 0.26(0.50) | ||
| Head rotation parameters | ||||
| FD_VanDijk | 0.05(0.03) | 0.04(0.03) | ||
| FD_Power | 0.18(0.08) | 0.16(0.09) | ||
| FD_Jenkinson | 0.09(0.04) | 0.09(0.05) |
Data are presented as the mean (standard deviation, SD). Abbreviations: CN, healthy controls; SCD, subjective cognitive decline; MMSE, Mini Mental State Examination; MoCA, Montreal Cognitive Assessment; MDRS, Mattis Dementia Rating Scale; HAMD, Hamilton Depression Scale; SCD-Q, Subjective Cognitive Decline-Questionnaire; ITV, intracranial volume;AVLT-IR, Auditory Verbal Learning Test – immediate recall; AVLT-5min-DR, Auditory Verbal Learning Test – 5-minute delayed recall; AVLT-20min-DR, Auditory Verbal Learning Test – 20-minute delayed recall; FD, framewise displacement. a Significant differences were found between CN and SCD subjects. MMSE, MoCA, and MDRS are displayed as raw scores. This study used the composite Z scores to indicate the level of each cognitive domain. Note: this study used a re-sampling method of stationary bootstrap (10,000 bootstrap samplings) to improve the statistical power.