Skip to main content
. 2020 Dec 3;13(1):1071–1095. doi: 10.18632/aging.202233

Table 2. Top 10 hub proteins in PPI network based on degree.

Gene name Degree Betweenness Centroid Closeness Bridging
UBA52 75 23277.55 -22 0.001153 32.12191
MAPK1 69 14795.83 9 0.001176 28.44867
HSPA8 56 14824.35 -14 0.001145 56.68246
ACTB 55 11072.69 -23 0.001142 40.24189
ACLY 52 14155.31 -159 9.90E-04 35.44649
APP 49 7938.799 -44 0.001119 36.50353
ACTN1 49 5651.568 -20 0.001144 38.92992
ACTN4 47 5555.22 -22 0.00114 43.87646
VWF 46 3615.55 -104 0.001048 35.02035
TGFB1 41 8255.129 -19 0.001151 58.37043

Degree, betweenness, centroid, closeness and bridging are algorithms provided by plugin Centiscape in software Cytoscape.