Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Nov 16;13(1):910–932. doi: 10.18632/aging.202202

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright: © 2020 Wen et al.

This is an open access article distributed under the terms of the Creative Commons Attribution License (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

PMC Copyright notice

Effects of the LOX-1, CD36 and SR-A1 siRNAs on oxLDL-induced IL-1β productions and effects of oxLDL and Tan IIA on LOX-1 expression and LOX-1-mediated caspase-1activation/IL-1β release. (A–C) Effects of lentivirus-mediated LOX-1, CD36 and SR-A1 siRNAs (MOI = 30) on oxLDL-induced IL-1β productions in mouse macrophages measured by ELISA. (D, E) Effects of oxLDL on LOX-1 expression in macrophages measured by qRT-PCR and Western blot, respectively. (F, G) Effects of Tan IIA on oxLDL-induced LOX-1 expression determined by qRT-PCR and Western blot, respectively. (H) Effects of Tan IIA on oxLDL-induced LOX-1-mediated IL-1β expression in macrophages. (I) Effects of Tan IIA on oxLDL-induced LOX-1-mediated caspase-1 activation in macrophages.