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Schematic Description of Stages 1–3 of Biofilm Formation.
Stage 1: Entry of multidrug-resistant pathogenic bacteria, commensals, and oral microflora. Stage 2: The salivary pellicle begins to form as the commensals and pathogenic bacteria congregate, laying the foundation for biofilm development. Stage 3: The bacteria rapidly multiply and begin to adhere, and dysbiosis begins.
