Table 2.
Conditional logistic regression of risk of dementia.
Crude OR | 95% C.I. | p-value | Adjusted OR† | 95% C.I. | p-value | |
---|---|---|---|---|---|---|
Allopurinol | 1.13 | 0.97–1.32 | 0.130 | 1.02 | 0.86–1.22 | 0.809 |
Benzbromarone | 0.82 | 0.70–0.96 | 0.013 | 0.81 | 0.68–0.97 | 0.021 |
Sulfinpyrazone | 1.13 | 0.80–1.59 | 0.487 | 1.27 | 0.88–1.85 | 0.205 |
Probenecid | 1.80 | 0.83–3.90 | 0.136 | 1.60 | 0.69–3.7 | 0.273 |
Hypertension | 1.56 | 1.29–1.87 | <0.001 | 1.20 | 0.97–1.47 | 0.087 |
Hyperlipidemia | 1.04 | 0.91–1.20 | 0.543 | 0.96 | 0.80–1.16 | 0.704 |
Chronic liver disease | 1.13 | 0.95–1.34 | 0.183 | 1.05 | 0.87–1.28 | 0.591 |
Chronic kidney disease | 1.36 | 1.10–1.68 | 0.005 | 1.20 | 0.94–1.51 | 0.137 |
Diabetes | 1.31 | 1.13–1.52 | <0.001 | 1.21 | 1.03–1.43 | 0.021 |
COPD | 1.40 | 1.20–1.65 | <0.001 | 1.31 | 1.10–1.55 | 0.003 |
Autoimmune disease | 1.26 | 0.86–1.84 | 0.245 | 1.27 | 0.84–1.92 | 0.257 |
Cardiovascular disease | 1.19 | 1.04–1.37 | 0.014 | 1.01 | 0.86–1.19 | 0.879 |
Stroke | 2.91 | 2.49–3.40 | <0.001 | 2.76 | 2.35–3.24 | <0.001 |
Depression | 4.44 | 3.37–5.87 | <0.001 | 3.45 | 2.57–4.63 | <0.001 |
Parkinson's disease | 4.20 | 3.03–5.81 | <0.001 | 2.88 | 2.02–4.10 | <0.001 |
Warfarin | 1.53 | 1.10–2.12 | 0.012 | 1.17 | 0.82–1.67 | 0.388 |
Statin | 1.11 | 0.96–1.29 | 0.141 | 0.94 | 0.77–1.14 | 0.515 |
COPD, Chronic obstructive pulmonary disease.
Adjusted for allopurinol, benzbromarone, sulfinpyrazone, probenecid, hypertension, hyperlipidemia, chronic liver disease, chronic kidney disease, diabetes, COPD, autoimmune disease, cardiovascular disease, stroke, depression, parkinson's disease, warfarin, and statin.