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. 2021 Jan 12;7:607808. doi: 10.3389/fmed.2020.607808

Table 2.

Conditional logistic regression of risk of dementia.

Crude OR 95% C.I. p-value Adjusted OR 95% C.I. p-value
Allopurinol 1.13 0.97–1.32 0.130 1.02 0.86–1.22 0.809
Benzbromarone 0.82 0.70–0.96 0.013 0.81 0.68–0.97 0.021
Sulfinpyrazone 1.13 0.80–1.59 0.487 1.27 0.88–1.85 0.205
Probenecid 1.80 0.83–3.90 0.136 1.60 0.69–3.7 0.273
Hypertension 1.56 1.29–1.87 <0.001 1.20 0.97–1.47 0.087
Hyperlipidemia 1.04 0.91–1.20 0.543 0.96 0.80–1.16 0.704
Chronic liver disease 1.13 0.95–1.34 0.183 1.05 0.87–1.28 0.591
Chronic kidney disease 1.36 1.10–1.68 0.005 1.20 0.94–1.51 0.137
Diabetes 1.31 1.13–1.52 <0.001 1.21 1.03–1.43 0.021
COPD 1.40 1.20–1.65 <0.001 1.31 1.10–1.55 0.003
Autoimmune disease 1.26 0.86–1.84 0.245 1.27 0.84–1.92 0.257
Cardiovascular disease 1.19 1.04–1.37 0.014 1.01 0.86–1.19 0.879
Stroke 2.91 2.49–3.40 <0.001 2.76 2.35–3.24 <0.001
Depression 4.44 3.37–5.87 <0.001 3.45 2.57–4.63 <0.001
Parkinson's disease 4.20 3.03–5.81 <0.001 2.88 2.02–4.10 <0.001
Warfarin 1.53 1.10–2.12 0.012 1.17 0.82–1.67 0.388
Statin 1.11 0.96–1.29 0.141 0.94 0.77–1.14 0.515

COPD, Chronic obstructive pulmonary disease.

Adjusted for allopurinol, benzbromarone, sulfinpyrazone, probenecid, hypertension, hyperlipidemia, chronic liver disease, chronic kidney disease, diabetes, COPD, autoimmune disease, cardiovascular disease, stroke, depression, parkinson's disease, warfarin, and statin.