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. 2021 Jan 25;6:15. doi: 10.1038/s41541-020-00277-1

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — Percentages of post-prime (upper panels) and post-protein boost (lower panels) cytokine-secreting CD4+ central/transitional memory T cells (T_CM/TM) were quantified in all four groups of monkeys following stimulation with C.1086 Env peptide pool. Percentages of IFN-γ (black circles), IL-2 (blue squares), TNF-α (green triangles), both IFN-γ/IL-2 (red inverted triangles) secreting T_CM/TM CD4+ T cells are shown for individual monkeys for each vaccine group with mean and SEM.