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. 2020 Jun 29;48(1):302–310. doi: 10.1007/s00259-020-04942-4

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© The Author(s) 2020

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Fig. 5 — Baseline Aβ-PET predicts subsequent change in PET data, driven by individuals with positive quantitation at baseline. Left: fast accumulation (> 5 Centiloids per year) was only observed in participants with Centiloid ≥ 26 at baseline. Note that no patients had a baseline Centiloid between 20 and 25. All participants but one (borderline) had a visually negative baseline PET, although four participants (designated with ×) had positive quantitation (Centiloid between 27.6 and 43.9). Right: illustrative PET images of a participant who demonstrated increased Aβ-PET signal during follow-up