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. 2021 Jan 25;12:582. doi: 10.1038/s41467-020-20828-3

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — Representative concentration–response curves showing the effect of UCB-9260 on signalling in an NFκβ reporter cell assay driven by 10 pM hTNF (blue trace), 100pM hTNF (green trace) and anti-TNFR1 antibody at 300 ng/mL (red trace). Source data are provided as a Source Data file.