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. 2021 Jan 12;11:618891. doi: 10.3389/fmicb.2020.618891

FIGURE 1.

FIGURE 1

Clinical characteristics and viral load in the collected organs. (A) Body weight changes in Syrian hamsters after viral infection at 0, 1, 3, 5, 7, 9, 11, 13, 14, 18, 21, 30, 33, 35, and 37 days post inoculation (dpi). The mock-infected hamsters were examined at 0, 1, 3, 5, and 7 dpi. (B) Viral RNA (log10 RNA copies/mL) by qRT-PCR assay detected in the throat swabs at 0, 1, 3, 5, and 7 dpi. (C) Viral RNA (log10 RNA copies/g) by qRT-PCR assay detected in the respiratory tract tissues and extrapulmonary organ tissues of SARS-CoV-2-challenged hamsters at 3, 5, and 7 dpi. Statistical significance in (A,B) was calculated between infected and mock-infected animals within each group. The data shown are the mean ± SEM. Statistical significance between groups was calculated by Student’s t-test (nsP > 0.05, ∗∗P < 0.01, ∗∗∗P < 0.001).