Fig. 1.

MXSGD component-targets network. (A)Two broad categories database: TCM database and literature resources. (B) 103 bioactive components screened by three criteria (red section represents the components of OB ≥30, yellow section represents DL ≥0.18, green section represents the components of Caco2 ≥-0.4), and 5 ingredients which do not meet the criteria but were included as major components of the herbal medicine, including 6 from Mahuang, 9 from Kuxingren, 5 from Shigao and 88 from Gancao. (C) Construction of MXSGD bioactive component-putative targets visual network. (For interpretation of the references to color in this figure legend, the reader is referred to the Web version of this article.)