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. 2021 Jan 12;8:590106. doi: 10.3389/fcell.2020.590106

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Copyright © 2021 Rapani, Nikiforaki, Karagkouni, Sfakianoudis, Tsioulou, Grigoriadis, Maziotis, Pantou, Voutsina, Pantou, Koutsilieris, Hatzigeorgiou, Pantos and Simopoulou.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Functional significance of miRNA targets in POR and AMA categories. The top 40 significantly enriched KEGG pathways, containing targeted genes for the upregulated set of miRNAs in each category, are portrayed. The X-axis depicts the number of miRNA-targeted genes enriching each term. Pathways are ranked according to the enrichment p-Value (p-Value < 0.01, Fisher’s exact test). The number of miRNAs implicated in each pathway is shown at the end of each bar. Intensity legend shows the p-value of each term. Common enriched pathways between the two categories are marked as bold.