TABLE 2.
Medications at hospital admission in worsening chronic heart failure according to left ventricular ejection fraction (available data in 4268 patients)
| Overall (n = 4268) | LVEF < 40% (n = 2254) | LVEF 40–49% (n = 864) | LVEF ≥ 50 (n = 1150) | P value | |
|---|---|---|---|---|---|
| ACEI (%) | 55.6 | 51.0 | 40.5 | 41.6 | <0.0001 |
| ARBs (%) | 13.5 | 13.2 | 14.0 | 10.7 | 0.83 |
| ACEI or ARBs (%) | 55.6 | 60.4 | 57.3 | 44.7 | <0.0001 |
| Beta‐blocker (%) | 38.5 | 42.5 | 37.4 | 31.3 | <0.0001 |
| Diuretics (%) | 54.4 | 58.0 | 50.9 | 49.9 | <0.0001 |
| Spironolactone (%) | 28.8 | 34.4 | 22.7 | 22.3 | <0.0001 |
| ACE/ARBs + beta‐blockers + spironolactone (%) | 11.4 | 16.0 | 7.9 | 5.0 | <0.0001 |
| ACE/ARBs + beta‐blockers (%) | 27.3 | 32.8 | 26.9 | 16.9 | <0.0001 |
| ACE/ARBs + spironolactone (%) | 19.9 | 25.4 | 14.0 | 13.6 | <0.0001 |
| None of the previous three (%) | 27.8 | 25.0 | 26.3 | 34.5 | <0.0001 |
ACEIs, angiotensin‐converting enzyme inhibitors; ARBs, angiotensin receptor blockers; LVEF, left ventricular ejection fraction.