Table 3.
Independent predictors for clinical outcomes after AF ablation
| Variables | Univariate | Multivariable | ||||
|---|---|---|---|---|---|---|
| HR | 95% CI | P value | HR | 95% CI | P value | |
| (A) All‐cause death | ||||||
| Age ≥75 years | 1.01 | 0.34–2.42 | 0.99 | |||
| Female | 0.68 | 0.29–1.45 | 0.33 | |||
| Persistent AF | 0.95 | 0.46–1.93 | 0.89 | |||
| Diabetes | 2.96 | 1.45–5.94 | 0.004 | 3.10 | 1.09–8.30 | 0.03 |
| LVDd ≥ 55 mm | 3.65 | 1.68–7.49 | 0.002 | 1.64 | 0.49–4.78 | 0.40 |
| LVEF < 50% | 1.52 | 0.73–3.21 | 0.26 | |||
| E/e′ ≥ 15 | 7.27 | 2.68–23.0 | <0.001 | 6.81 | 2.47–21.8 | <0.001 |
| BNP ≥ 200 pg/dL | 2.05 | 0.96–4.78 | 0.06 | 2.65 | 0.67–17.6 | 0.18 |
| LAD ≥ 40 mm | 2.33 | 0.91–7.88 | 0.08 | 2.31 | 0.49–18.3 | 0.31 |
| Moderate‐to‐severe MR | 2.12 | 0.96–4.36 | 0.06 | 1.68 | 0.49–5.00 | 0.39 |
| Recurrent AF after procedure | 1.46 | 0.69–2.96 | 0.31 | |||
| (B) Heart failure hospitalization | ||||||
| Age ≥75 years | 2.65 | 1.22–5.43 | 0.02 | 0.74 | 0.16–2.43 | 0.65 |
| Female | 0.80 | 0.35–1.69 | 0.58 | |||
| Persistent AF | 1.28 | 0.63–2.63 | 0.49 | |||
| Diabetes | 2.56 | 1.21–5.21 | 0.02 | 2.55 | 0.85–7.02 | 0.09 |
| LVDd ≥ 55 mm | 4.29 | 2.02–8.76 | <0.001 | 2.44 | 0.80–6.91 | 0.11 |
| LVEF < 50% | 1.27 | 0.62–2.59 | 0.51 | |||
| E/e′ ≥ 15 | 2.85 | 1.05–7.78 | 0.04 | 2.95 | 1.03–8.46 | 0.04 |
| BNP ≥ 200 pg/dL | 2.25 | 1.02–5.66 | 0.04 | 2.00 | 0.61–9.17 | 0.27 |
| LAD ≥ 40 mm | 2.78 | 0.99–11.7 | 0.054 | 1.80 | 0.33–33.3 | 0.55 |
| Moderate‐to‐severe MR | 1.83 | 0.80–3.85 | 0.15 | |||
| Recurrent AF after procedure | 3.11 | 1.53–6.42 | 0.002 | 1.93 | 0.66–5.38 | 0.22 |
AF, atrial fibrillation; BNP, B‐type natriuretic peptide; CI, confidence interval; HR, hazard ratio; LAD, left atrial dimension; LVDd, left ventricular diastolic dimension; LVEF, left ventricular ejection fraction; MR, mitral regurgitation.