Table 2.

Multivariate analysis of heart failure duration and other factors independently associated with white matter lesions (Fazekas 2 and 3)

Factors	Odds ratio	P‐value	Confidence interval (95%)
Gender (female)	1.1	0.660	(0.8–1.4)
Age	1.094	≤0.001	(1.074–1.114)
Stroke	2.0	0.034	(1.0–3.9)
Hypertension	2.0	≤0.001	(1.5–2.7)
Heart failure (no vs. ≤3 years after diagnosis)	0.8	0.811	(0.1–7.5)
Heart failure (no vs. 4–6 years after diagnosis)	1.6	0.580	(0.3–9.6)
Heart failure (no vs. >6 years after diagnosis)	2.9	0.036	(1.1–7.9)

BMI, body mass index.

A longer duration of heart failure ≥6 years was associated with severe white matter lesions.