Table 1.
Study site | Area | Type of area | Study period (mm/yy) |
Median (range) deliveries per week by women living with HIV | Median (range) DBS collected per week for EID | Eligible participants | Timing of follow-up | Staff trained to perform LYNX assay |
---|---|---|---|---|---|---|---|---|
Livingstone Central Hospital | Livingstone City | Urban |
06/16–05/17 06/17–04/18 |
8 (1, 15) | N/A |
All HEI High-risk HEIa |
Birth only | 1 Research staffc |
Maramba UHC | Livingstone City | Urban |
06/16–05/17 06/17–04/18 |
3 (0, 12) | N/A |
All HEI High-risk HEIa |
Birth only | 1 Research staffc |
Mahatma Gandhi UHC | Livingstone City | Urban | 04/17–04/18 | 3 (0, 9) | N/A | High-risk HEIa | Birth only | 1 Research staffc |
Libuyu UHC | Livingstone City | Urban | 04/17–04/18 | 1 (0, 5) | N/A | High-risk HEIa | Birth only | 1 Research staffc |
Choma General Hospital | Choma City | Urban | 08/17–04/18 | 5 (2, 9) | N/A | High-risk HEIa | Birth only | 2 Nurses |
Shampande UHC | Choma City | Urban | 08/17–04/18 | 2 (0, 5) | N/A | High-risk HEIa | Birth only | 2 Nurses |
Macha Hospital | Macha area | Rural | 04/16–09/18 | 2 (0, 9) | 3 (0, 11) | All HEI | Testing periodb |
5 Counselors 6 Research staffc |
Mapanza RHC | Macha area | Rural | 04/16–09/18 | 0 (0, 4) | 1 (0, 7) | All HEI | Testing periodb |
1 Clinical Officer 2 Nurses 1 Counselor |
Moboola RHC | Macha area | Rural | 04/16–09/18 | 0 (0, 3) | 1 (0, 7) | All HEI | Testing periodb |
2 Nurses 1 Counselor |
Mangunza RHC | Macha area | Rural | 04/16–09/18 | 0 (0, 3) | 1 (0, 5) | All HEI | Testing periodb |
1 Nurse 1 Counselor |
Nalube RHC | Macha area | Rural | 04/16–07/17 | 0 (0, 2) | 0 (0, 3) | All HEI | Testing periodb |
1 Nurse 1 Counselor |
DBS Dried blood spots, EID Early infant diagnosis, HEI HIV-exposed infants, N/A Not applicable, RHC Rural health clinic, UHC Urban health center
a High-risk defined as mothers receiving no antiretroviral drugs throughout pregnancy or starting to receive antiretroviral drugs during pregnancy to prevent mother-to-child transmission
b Testing period includes any point of contact for early infant diagnosis testing from birth to post-weaning (e.g. birth, 6 weeks, 6 months, 12 months, 18 months, 24 months, post-weaning)
c Research staff in Livingstone included 3 nurses; research staff in Macha included 1 nurse, 1 laboratory scientist, and 4 counselors by training