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. 2021 Jan 12;11:609234. doi: 10.3389/fneur.2020.609234

Table 3.

Predictive performance of the risk score for ischemic brain lesions.

CHA2D-VASc score* CHA2DS2-VASc score
Clinically overt ischemic brain lesions
C-statistic 0.622 NA
Brier Score 0.093 NA
AIC 1,147 NA
Silent ischemic brain lesions
C-statistic 0.582 NA
Brier Score 0.174 NA
AIC 1,852 NA
Any ischemic brain lesion
C-statistic 0.626 0.693
Brier Score 0.223 0.207
AIC 2,217 2,099

AIC, Akaike's Information Criteria; NA, not applicable.

*

CHA2D-VASc score was adapted by excluding history of stroke/transient ischemic attack (S2).

Female patients with a CHA2D-VASc score/CHA2DS2-VASc score of 1 were assigned to the category of 0 points.

Clinically overt ischemic brain lesions were defined as ischemic brain lesions in patients with a history of stroke.

Silent ischemic brain lesions were defined as ischemic brain lesions in patients without a history of stroke/TIA.

Any ischemic brain lesion was defined as a composite of clinically overt and silent ischemic brain lesions including ischemic lesions in patients with history of TIA.