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. 2021 Jan 19;22(2):975. doi: 10.3390/ijms22020975

Table 1.

Examples for the involvement of PP2A (PP1) in vesicle traffic of plant cells. See text for more details.

Subunit Involved Change of Protein Phosphatase Activity or Other PP2A Related Functions Target Protein Function References
PP2A/C activation MAP65-1 MAP65-3? Bundling of MTs, indirect regulation of vesicle traffic [9,30]
PP2A/C activation AMPK, activation Blocking of TORC pathway, triggering of autophagy [56]
TAP46 subunit of PP2A activation proteins of the TORC pathway Triggering of the TORC pathway and blocking of autophagy pathway [4,51]
Methylation of PP2A/C by SBI1 SBI1 targets PP2A to BRI1 containing endosomes BRI1 Dephosphorylation of excess BRI1 that will be targeted to lytic vacuoles [4,62]
PP2A/B’, C inhibition/deactivation BZR1 BZR1 remains phosphorylated, thus targeted to the autophagy pathway [65,100]
PP2A/A, C3, C4, PP1 activation PINs, dephosphorylation PIN recycling and proper membrane localization. Polar transport-tissue distribution of auxins [69,70,76,87,98]

AMPK—AMP-activated Ser kinase; BRI1—brassinosteroid (BR) receptor; BZR1—BR induced transcription factor; SBI1—leucine carboxymethylase.