Table 2.
Comparison of patient’s characteristics by subgroups.
| Characteristics | |||
|---|---|---|---|
| Variables | PARP Positive | PARP Negative | p-Value |
| Number of patients (n = 104; 100%) | 70 (67.31%) | 34 (32.69%) | - |
| Mean age (years) | 59.01 ± 10.37 years | 55.71 ± 12.55 years | 0.158 |
| Histological type | |||
| Serous | 68/70 (97.14%) | 32/34 (94.12%) | 0.454 |
| other | 2/70 (2.86%) | 2/34 (6.88%) | |
| Grade (2-tier) | |||
| High | 70/70 (100%) | 34/34 (100%) | 1 |
| Stage | |||
| Early (FIGO IIIA») | 8/70 (11.43%) | 7/34 (20.59%) | 0.41 |
| Advanced (FIGO IIIB«) | 62/70 (88.57%) | 27/34 (79.41%) | |
| Bulky lymph node metastasis | |||
| Yes | 21/70 (30.00%) | 12/34 (35.29%) | 0.59 |
| No | 49/70 (70.00%) | 22/34 (64.71%) | |
| Primer debulking surgery | |||
| with no residual disease (R0) | 36/70 (51.43%) | 20/34 (58.82%) | 0.48 |
| with residual disease (R1) | 34/70 (48.57%) | 14/34 (41.18%) | |
| BRCA status | |||
| positive | 20/70 (28.57%) | 11/34 (32.35%) | 0.694 |
| negative | 50/70 (71.43%) | 23/34 (67.65%) | |
| No of relapse | 60/70 (85.71%) | 26/34 (76.47%) | 0.245 |
| Median PFS | 11.9 months | 20.1 months | 0.001 |
| No of death | 28/70 (40%) | 12/34 (35.29%) | 0.646 |
| Median OS | 49 months | 114 months | 0.014 |