Table 1.

Baseline demographic and clinical characteristics of the study population.

	H. pylori * Negative Subjects	H. pylori * Positive Subjects	p-Value	Effect Size
	(No. 74,843)	(No. 75,640)
Age: Mean (SD), in years	42.15 (±16.65)	40.95 (±14.72)	<0.0001	−0.08
Females	50%	49%	<0.001	−0.02
BMI (kg/m2)	26.45 (±5.62)	26.89 (±5.64)	<0.0001	0.08
Smoking	0.16	0.22	<0.0001	0.15
Hypertension	0.08	0.06	<0.0001	−0.09
Type 2 Diabetes Mellitus	0.07	0.06	<0.0001	−0.04
Ischemic Heart Disease	0.04	0.03	<0.0001	−0.07
Congestive Heart Failure	0.01	0.01	<0.0001	−0.05
Atrial Fibrillation	0.02	0.01	<0.0001	−0.06
Crohn’s Disease	0.01	0.01	<0.0001	−0.06
Ulcerative Colitis	0.01	0.00	<0.0001	−0.04
Irritable Bowel Syndrome	0.10	0.07	<0.0001	−0.14
Liver Diseases (any type)	0.05	0.04	<0.0001	−0.06
Non-Alcoholic Fatty Liver Disease	0.05	0.04	<0.0001	−0.06
Hypothyroidism	0.09	0.07	<0.0001	−0.08
Osteoporosis	0.13	0.09	<0.0001	−0.11
Recent Omeprazole Use	0.03	0.02	<0.0001	−0.04
Recent Esomeprazole Use	0.04	0.02	<0.0001	−0.09

* H. pylori—Helicobacter Pylori.