Table 1.
Composition of six prototype toothpastes used in the in vitro preliminary testing. The prototypes in bold (258, C58) were applied as enzymatic-containing toothpastes in the randomized clinical trial.
| Prototype | Enzymes (%) |
D-Glucose (%) | Vitamin C (%) | Sodium Bisulfite (%) | SCN− (%) |
Citrox (%) |
|---|---|---|---|---|---|---|
| 000 | 0 | 0 | 0 | 0 | 0 | 0 |
| 255 * | GOX 0.5 | 1 | 0.1 | 0 | 0 | 0 |
| 755 * | GOX 0.25 LPO 0.25 |
0.4 | 0.004 | 0 | 0.1 | 0 |
| 258 * | GOX 0.5 | 1 | 0 | 0.2 | 0 | 0 |
| C00 | 0 | 0 | 0 | 0 | 0 | 1 |
| C58 * | GOX 0.5 | 1 | 0 | 0.2 | 0 | 1 |
GOX = glucose oxidase; LPO = lactoperoxidase; SCN− = thiocyanate; * prototype manufacturing under oxygen exclusion in glove boxes.