Table 2. Logistic Regression Models for COVID-19 Outcomes by Smoking Status Among the Cohort.

Outcome	Odds ratio (95% CI)
	Unadjusted	Adjusted for age, race, and gender	Adjusted for age, race, gender, medication,a and comorbidityb
Hospitalization given a positive COVID-19 test
Never smoker	1 [Reference]	1 [Reference]	1 [Reference]
0-10 Pack-years	1.41 (1.10-1.81)	0.99 (0.76-1.30)	0.96 (0.70-1.30)
10-30 Pack-years	2.48 (2.01-3.07)	1.41 (1.12-1.78)	1.16 (0.85-1.58)
>30 Pack-years	4.65 (3.72-5.82)	2.25 (1.76-2.88)	2.19 (1.52-3.14)
ICU admission given a positive COVID-19 test and hospitalization
Never smoker	1 [Reference]	1 [Reference]	1 [Reference]
0-10 Pack-years	1.33 (0.84-2.08)	1.19 (0.75-1.89)	1.08 (0.65-1.79)
10-30 Pack-years	1.74 (1.23-2.45)	1.55 (1.09-2.21)	1.34 (0.86-2.13)
>30 Pack-years	2.11 (1.54-2.89)	1.69 (1.23-2.35)	1.34 (0.86-2.10)
Death given a positive COVID-19 test
Never smoker	1 [Reference]	1 [Reference]	1 [Reference]
0-10 Pack-years	2.38 (1.50-3.80)	1.66 (0.98-2.83)	1.07 (0.59-1.94)
10-30 Pack-years	3.40 (2.31-5.02)	1.47 (0.96-2.27)	0.88 (0.51-1.52)
>30 Pack-years	6.11 (4.33-8.61)	1.89 (1.29-2.76)	1.26 (0.75-2.10)
Per pack-year
Hospitalization	1.030 (1.026-1.034)	1.015 (1.011-1.019)	1.013 (1.007-1.019)
ICU admission	1.012 (1.007-1.016)	1.008 (1.003-1.013)	1.005 (0.999-1.012)
Death	1.026 (1.020-1.031)	1.007 (1.002-1.013)	1.003 (0.995-1.010)

Abbreviations: COVID-19, coronavirus disease 2019; ICU, intensive care unit.

^aAngiotensin receptor blockers and oral or inhaled corticosteroids.

^bCoronary artery disease, chronic obstructive pulmonary disease or emphysema, hypertension, and diabetes.