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Altered levels of VEGFR2 phosphorylation from patient amniocytes (A), endothelial cells (EC) and co-cultured amniocytes and endothelial cells (EC+A). Ratio of phosphorylated (p) VEGFR2 at tyrosine 1175 versus total VEGFR2 were altered in endothelial cell (EC) when co-cultured with patient cells (3.4-fold) compared to endothelial cells co-cultured with control cells (1.3). SMA is an amniocyte marker.
