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[Preprint]. 2021 Jan 19:2021.01.19.426885. [Version 1] doi: 10.1101/2021.01.19.426885

Figure 3. Humoral immune responses in NHPs.

Figure 3.

Serum samples collected throughout the study from all NHPs were examined for (A) SARS-CoV-2 S-specific IgG, (B) SARS-CoV-2 S receptor binding domain (RBD)-specific IgG or (C) IgG subclasses specific to SARS-CoV-2 S by ELISA. (D) Neutralizing titers to SARS-CoV-2 were determined. (E) Bronchoalveolar lavage (BAL) samples were analyzed for SARS-CoV-2 S-specific IgG (S IgG) or IgA (S IgA), and SARS CoV-2 S RBD-specific IgG (RBD IgG) by ELISA. (A-D) Geometric mean and geometric standard deviation (SD) are depicted. (F) IgG subclasses specific to SARS-CoV-2 S in BAL samples were analyzed by ELISA. (E, F) Mean and SD are depicted. Statistical significance is indicated.