Table 2.
Baseline characteristics of AIS patients according to PLT tertiles
| Variables | PLT tertiles | |||
|---|---|---|---|---|
| Tertile1 (n=193) | Tertile2 (n=187) | Tertile3 (n=190) | P-value | |
| PLT (×109/L) | < 175 | 175–222 | > 222 | |
| HT, n (%) | 123 (63.7%) | 80 (42.8%) | 82 (43.2%) | < 0.001 |
| Demographic characteristics | ||||
| Age (years) | 70.2 ± 11.6 | 68.9 ± 12.7 | 67.5 ± 12.8 | 0.970 |
| Male, n (%) | 147 (76.2%) | 130 (69.5%) | 111 (58.4%) | 0.590 |
| Baseline SBP (mmHg) | 150.0 ± 22.2 | 157.8 ± 21.8 | 152.3 ± 24.5 | < 0.001 |
| Baseline DBP (mmHg) | 81.6 ± 14.0 | 83.2 ± 14.2 | 82.2 ± 13.2 | 0.732 |
| NIHSS on admission, median (IQR) | 5.0 (3.0–11.0) | 4.5 (2.0–9.0) | 5.0 (2.0–9.0) | 0.028 |
| CTA, n (%) | 16 (8.3%) | 26 (13.9%) | 22 (11.6%) | 0.218 |
| Vascular risk factors, n (%) | ||||
| Current smoking | 64 (33.2%) | 64 (34.2%) | 82 (43.2%) | 0.028 |
| Current drinking | 80 (41.5%) | 74 (39.6%) | 74 (38.9%) | < 0.001 |
| Previous Stroke | 26 (13.5%) | 20 (10.7%) | 26 (13.7%) | 0.207 |
| Hypertension | 115 (59.6%) | 132 (70.6%) | 129 (67.9%) | 0.112 |
| Diabetes | 45 (23.3%) | 56 (29.9%) | 48 (25.3%) | 0.294 |
| CAD | 23 (11.9%) | 14 (7.5%) | 10 (5.3%) | 0.010 |
| Dyslipidemia | 12 (6.2%) | 13 (7.0%) | 12 (6.3%) | 0.610 |
| AF | 63 (32.6%) | 41 (21.9%) | 33 (17.4%) | < 0.001 |
| Hematological variables | ||||
| Leukocyte counts (×109/L) | 7.4 ± 2.8 | 7.8 ± 3.0 | 7.8 ± 2.6 | < 0.001 |
| Erythrocyte counts (×109/L) | 4.4 ± 0.6 | 4.5 ± 0.6 | 4.4 ± 0.5 | 0.836 |
| MPV (fl) | 11.3 ± 1.5 | 10.9 ± 1.4 | 10.6 ± 1.2 | 0.007 |
| PT (s) | 14.0 ± 1.1 | 13.6 ± 1.0 | 13.5 ± 1.0 | < 0.001 |
| INR | 1.1 ± 0.1 | 1.0 ± 0.1 | 1.0 ± 0.1 | < 0.001 |
| FIB (g/L) | 3.7 ± 1.2 | 3.7 ± 1.1 | 4.0 ± 2.3 | < 0.001 |
| Stroke etiology, n (%) | < 0.001 | |||
| Atherosclerosis | 126 (68.4%) | 137 (73.3%) | 142 (74.7%) | |
| Cardioembolism | 51 (26.4%) | 29 (15.5%) | 29 (15.3%) | |
| Small vessel occlusion | 2 (1.0%) | 1 (0.5%) | 1 (0.5%) | |
| Other causes | 6 (3.1%) | 8 (4.2%) | 4 (2.1%) | |
| Treatment, n (%) | ||||
| Anticoagulant therapy | 61 (31.6%) | 26 (13.9%) | 27 (14.2%) | < 0.001 |
| Antiplatelet therapy | 122 (63.2%) | 150 (80.2%) | 142 (74.7%) | < 0.001 |
Abbreviations: PLT, platelet counts; HT, hemorrhagic transformation; SBP, systolic blood pressure; DBP, diastolic blood pressure; NIHSS, National Institute of Health Stroke Scale; CTA, computered tomograhy angiography; CAD, coronary artery disease; AF, atrial fibrillation; MPV, mean platelet volume; PT, prothrombin time; INR, International Normalized Ratio; FIB, fibrinogen