Table 3.

Multivariate logistic regression analysis of predictive factors for HT in all patients

	Model 1		Model 2		Model 3
	adjust OR(95%CI)	P-value	adjust OR(95%CI)	P-value	adjust OR(95%CI)	P-value
PLT
T1	2.002 (1.160–3.454)	0.013	3.887 (1.762–8.575)	0.001	3.517 (1.526–8.106)	0.003
T2	1.055 (0.617–1.803)	0.845	1.425 (0.710–2.861)	0.319	1.525 (0.738–3.149)	0.254
T3	Ref		Ref		Ref
MPV	–	–	0.714 (0.573–0.890)	0.003	0.698 (0.557–0.875)	0.002
PT	–	–	3.624 (1.015–12.939)	0.047	3.599 (0.941–13.767)	0.061
INR	–	–	0.904 (0.796–1.027)	0.121	0.904 (0.791–1.035)	0.143
FIB	–	–	1.570 (1.191–2.069)	0.001	1.613 (1.199–2.169)	0.002

Notes: Model 1: adjusted sex, age, smoking, drinking, CAD, AF, baseline SBP, NIHSS on admission; Model 2: adjusted for covariates from Model 1 and further adjusted for MPV, PT, INR, FIB and leukocyte counts; Model 3: adjusted for covariates from Model 2 and further adjusted for anticoagulant therapy and antiplatelet therapy

Abbreviations: CI, confidence interval; OR, odds ratio; HT, hemorrhagic transformation; PLT, platelet counts; MPV, mean platelet volume; PT, prothrombin time; INR, International Normalized Ratio; FIB, fibrinogen