Table 4.

Multivariate logistic regression analysis of predictive factors for HT after subcategorized by AF

	Non-AF						AF
	Model 1		Model 2		Model 3		Model 1		Model 2		Model 3
	adjust OR (95%CI)	P-value	adjust OR (95%CI)	P-value	adjust OR (95%CI)	P-value	adjust OR (95%CI)	P-value	adjust OR (95%CI)	P-value	adjust OR (95%CI)	P-value
PLT
T1	2.236 (1.220–4.095)	0.009	4.908 (1.930–12.481)	0.001	3.509 (1.268–9.711)	0.016	1.894 (0.467–7.685)	0.371	3.084 (0.448–21.206)	0.252	4.822 (0.561–41.468)	0.152
T2	0.920 (0.508–1.666)	0.784	1.383 (0.626–3.058)	0.423	1.344 (0.575–3.143)	0.496	1.985 (0.440–8.947)	0.372	1.885 (0.289–12.320)	0.508	1.873 (0.262–13.378)	0.532
T3	Ref		Ref		Ref		Ref		Ref		Ref
MPV	–	–	0.620 (0.479–0.804)	< 0.001	0.605 (0.455–0.805)	0.001	–	–	1.118 (0.635–1.968)	0.700	1.134 (0.648–1.985)	0.659
PT	–	–	3.774 (0.886–16.074)	0.072	3.500 (0.721–16.997)	0.120	–	–	2.865 (0.093–88.653)	0.548	3.861 (0.102–146.521)	0.466
INR	–	–	0.901 (0.778–1.042)	0.159	0.908 (0.774–1.065)	0.237	–	–	0.927 (0.660–1.304)	0.665	0.902 (0.627–1.298)	0.580
FIB	–	–	1.838 (1.324–2.551)	< 0.001	1.928 (1.346–2.760)	< 0.001	–	–	1.023 (0.726–1.441)	0.897	1.061 (0.735–1.533)	0.752

Notes: Model 1: adjusted sex, age, smoking, drinking, CAD, AF, baseline SBP, NIHSS on admission; Model 2: adjusted for covariates from Model 1 and further adjusted for MPV, PT, INR, FIB and leukocyte counts; Model 3: adjusted for covariates from Model 2 and further adjusted for anticoagulant therapy and antiplatelet therapy

Abbreviations: CI, confidence interval; OR, odds ratio; HT, hemorrhagic transformation; AF, atrial fibrillation; PLT, platelet counts; MPV, mean platelet volume; PT, prothrombin time; INR, International Normalized Ratio; FIB, fibrinogen