Table 2.
Multivariate analysis for exploring potential risk factors for prognosis of AEG
| Characteristics | Initial multivariate model | Final multivariate model | |||
|---|---|---|---|---|---|
| SHR (95% CI) | P | beta | SHR (95% CI) | P | |
| Age (year) | |||||
| < 60 | Reference | Reference | |||
| ≥ 60 | 1.393 (1.223–1.588) | < 0.001 | 0.329 | 1.389 (1.220–1.583) | < 0.001 |
| T stage | |||||
| T1 | Reference | Reference | |||
| T2 | 1.604 (1.204 -2.137) | < 0.001 | 0.465 | 1.592 (1.211–2.093) | < 0.001 |
| T3 | 2.207 (1.698–2.869) | < 0.001 | 0.773 | 2.167 (1.710–2.747) | < 0.001 |
| T4 | 2.606 (1.990–3.411) | < 0.001 | 0.938 | 2.555 (2.000–3.265) | < 0.001 |
| N stage | |||||
| N0 | Reference | Reference | |||
| N1 | 1.831 (1.525–2.198) | < 0.001 | 0.596 | 1.814 (1.515–2.172) | < 0.001 |
| N2 | 2.536 (2.089–3.077) | < 0.001 | 0.918 | 2.505 (2.073–3.028) | < 0.001 |
| N3 | 3.417 (2.750–4.247) | < 0.001 | 1.205 | 3.335 (2.702–4.116) | < 0.001 |
| Grade | |||||
| Low grade | Reference | Reference | |||
| High grade | 1.277 (1.120–1.457) | < 0.001 | 0.248 | 1.281 (1.124–1.460) | < 0.001 |
| Number of examined lymph nodes | |||||
| < 5 | Reference | Reference | |||
| < 10 | 0.736 (0.555–0.975) | 0.032 | − 0.286 | 0.751 (0.569–0.993) | 0.040 |
| < 15 | 0.630 (0.477–0.832) | 0.001 | − 0.455 | 0.635 (0.481–0.838) | 0.013 |
| ≥ 15 | 0.535 (0.410–0.698) | < 0.001 | − 0.616 | 0.540 (0.414–0.704) | < 0.001 |
| Race | |||||
| White | Reference | ||||
| Black | 0.973 (0.713–1.329) | 0.860 | |||
| Others | 0.829 (0.662–1.039) | 0.100 | |||
| Sex | |||||
| Female | Reference | ||||
| Male | 0.965 (0.825–1.129) | 0.660 | |||
| Size (cm) | |||||
| < 1.0 | Reference | ||||
| < 2.0 | 1.179 (0.732–1.899) | 0.500 | |||
| < 3.0 | 1.087 (0.682–1.731) | 0.730 | |||
| < 5.0 | 1.121 (0.707–1.777) | 0.630 | |||
| ≥ 5.0 | 1.048 (0.659–1.668) | 0.840 | |||
SHR sub-distribution hazard ratio, CI confidential interval