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. 2021 Jan 26;40:45. doi: 10.1186/s13046-021-01854-5

Fig. 1.

Fig. 1

LINC00680 is upregulated in HCC, predicting poor prognosis of HCC patients. a. The heatmap of the differentially expressed LncRNAs between adjacent normal liver tissues (51 cases) and HCC tissues (370 cases) across TCGA database. b. Comparison of LINC00680 expression between 370 HCC tissues and 51 adjacent normal liver tissues based on TCGA dataset. c. The receiver operator characteristic (ROC) analysis determining the diagnostic value of LINC00680 expression level in differentiating between normal and malignant hepatic tissues using data from TCGA LIHC dataset. d. Expression of LINC00680 between 74 pairs of HCC tumor tissues and adjacent normal liver tissues. e. Relative expression of LINC00680 in HCC cell lines and L02 cells. f, g. Kaplan-Meier analyses for the correlation between the LINC00680 level and HCC prognoses in 74 patients (f. Overall survival; g. Disease free survival). **P < 0.01