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. 2021 Jan 26;40:45. doi: 10.1186/s13046-021-01854-5

Fig. 2.

Fig. 2

The LINC00680 regulates stemness properties in HCC cells. a, b. Analysis of the level of stemness-associated genes, including CD133, OCT4, NANOG and SOX-2 in LINC00680 knockdown SNU-449 and SK-hep1 cells, and LINC00680 overexpressed Huh7 cells by Western blot (a) and qRT-PCR (b), respectively. c. Statistical analysis of the primary and secondary sphere formation capacities in LINC00680 knockdown SNU-449 and SK-hep1 cells, and LINC00680 overexpressed Huh7 cells (upper panel) with the representative images showing secondary sphere formation in these cells (lower panel). **P < 0.01